What does this research mean for the field?

Safe anesthetic care for patients with Myoclonic epilepsy with ragged red fibers (MERRF) can be achieved through individualized strategies including cautious selection of anesthetic agents, strict metabolic control, and avoidance of lactate-containing solutions. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe safe anesthetic and perioperative management strategies for a patient with myoclonic epilepsy with ragged red fibers (MERRF) undergoing surgery.

August 22, 2026Anesthesia and Pain MedicineOpen Access

Anesthetic management of patient with myoclonic epilepsy with ragged red fibers, a mitochondrial disease - A case report -

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Authors

YKYunho KangUlsan College BKBo-eun KimUlsan College JKJi Hyeon KimKorea University

Discussion

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Implication

Case report demonstrates safe anesthetic management in a patient with MERRF syndrome, indicating the value of tailored drug dosing and metabolic monitoring.

Key Points

To describe safe anesthetic and perioperative management strategies for a patient with myoclonic epilepsy with ragged red fibers (MERRF) undergoing surgery.
Administered general anesthesia to a 44-year-old female with MERRF undergoing unilateral salpingo-oophorectomy (N=1).
Induced anesthesia with low-dose midazolam, remifentanil, and rocuronium, and maintained with desflurane and remifentanil while maintaining normothermia and avoiding lactate-containing fluids.
Achieved an uneventful intraoperative and immediate postoperative course without metabolic, cardiac, or respiratory complications.
Prevented mitochondrial decompensation through individualized anesthetic selection, strict metabolic control, and comprehensive monitoring.

Cite This Study

Kang et al. (2026) studied this question.

synapsesocial.com/papers/6a895f2aca7ade938187d975 https://doi.org/10.17085/apm.26610

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Implication

Case report demonstrates safe anesthetic management in a patient with MERRF syndrome, indicating the value of tailored drug dosing and metabolic monitoring.

Anesthetic management of patient with myoclonic epilepsy with ragged red fibers, a mitochondrial disease - A case report -

Discussion

Member takes

Implication

Key Points

Cite This Study

Anesthetic management of patient with myoclonic epilepsy with ragged red fibers, a mitochondrial disease - A case report -

Discussion

Member takes

Implication

Key Points

Cite This Study

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