What does this research mean for the field?

No single preventive or therapeutic method is universally effective for postoperative seroma in breast cancer patients, requiring a comprehensive and individualized management approach based on surgical strategy, tissue healing, and patient status. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate current preventive and therapeutic strategies for postoperative seroma in breast cancer surgery, analyzing surgical techniques, dead space closure, and drainage optimization.

August 22, 2026Journal of Investigative SurgeryOpen Access

Prevention and Management of Postoperative Seroma in Patients with Breast Cancer: A Narrative Review

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To evaluate current preventive and therapeutic strategies for postoperative seroma in breast cancer surgery, analyzing surgical techniques, dead space closure, and drainage optimization.
Synthesized current literature on seroma pathogenesis, risk factors, modern surgical instruments, and postoperative drainage protocols.
Seroma formation is driven by combined localized inflammatory responses and mechanical lymphatic trauma.
Preventive interventions, including fibrin sealants, early drain removal, and flap fixation, exhibit varying degrees of efficacy across surgical settings.
Standard management continues to rely primarily on repeated percutaneous aspiration punctures alongside active prevention of secondary infections.

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Implication

Narrative review reveals variable efficacy among seroma prevention strategies in breast cancer surgery, indicating the need for tailored multimodal care.

Cite This Study

Samusieva et al. (2026) studied this question.

synapsesocial.com/papers/6a895f2aca7ade938187d9ba https://doi.org/10.1080/08941939.2026.2719252

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Implication

Narrative review reveals variable efficacy among seroma prevention strategies in breast cancer surgery, indicating the need for tailored multimodal care.

Prevention and Management of Postoperative Seroma in Patients with Breast Cancer: A Narrative Review

Key Points

Discussion

Implication

Cite This Study

Prevention and Management of Postoperative Seroma in Patients with Breast Cancer: A Narrative Review

Key Points

Discussion

Implication

Cite This Study

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