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August 22, 2026Journal of Binocular Vision and Ocular Motility

Sixth Cranial Nerve Paresis Secondary to Intracranial Hypotension: Etiology, Clinical Characteristics, and Treatment

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Authors

PMP. MerinoAFAriana FuentesLBL. Bermejo

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Overview

Case report reveals reversible sixth cranial nerve paresis caused by intracranial hypotension after anesthesia, highlighting the importance of orthostatic headache for early diagnosis.

Key Points

  • To review the etiology, clinical manifestations, radiological features, and therapeutic strategies for sixth cranial nerve palsy resulting from intracranial hypotension.
  • Evaluated two young women presenting to the emergency department with acute unilateral sixth cranial nerve paresis and diplopia following anesthetic procedures.
  • Performed clinical, neurological, and radiological assessments to confirm cerebrospinal fluid hypovolemia and associated intracranial changes.
  • Both patients demonstrated clinical and neuroimaging evidence of cerebrospinal fluid deficit, with one patient displaying bilateral subdural fluid collections.
  • One case achieved complete symptom resolution after receiving an epidural blood patch, while the second case resolved spontaneously with conservative management.

Cite This Study

Merino et al. (2026) studied this question.

synapsesocial.com/papers/6a895f74ca7ade938187e26ahttps://doi.org/10.1080/2576117x.2026.2718672
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