Experimental study demonstrates tandem-activated DNA nanosystems for in situ imaging of mitochondrial ATP and microRNA, highlighting improved spatial precision during drug interventions.
A precision engineered DNA nanosystem integrates mitochondria targeting with tandem activated signal amplification, enabling in situ imaging of ATP fluctuations in mitochondria following drug intervention and correlated monitoring of ATP and microRNA. More in the Research Article e5242162, Lele Li, Mengyuan Li, and co-workers.
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Feng et al. (2026) studied this question.
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