Why the study?
Is body mass index associated with type 2 diabetes mellitus and insulin resistance in an elderly Chinese population?
Is body mass index associated with type 2 diabetes mellitus and insulin resistance in an elderly Chinese population?
Higher BMI is associated with increased insulin resistance and decreased insulin sensitivity in elderly Chinese patients with type 2 diabetes mellitus.
Supports weight management as a potential metabolic target in elderly Chinese patients; confirms established adiposity risks while.
Background: There is limited information on the association between metabolic syndrome components including body mass index (BMI) and type 2 diabetes mellitus in elderly Chinese population. Therefore, we investigated whether components of metabolic syndrome are associated with type 2 diabetes mellitus in elderly. Methods: A total of 479 hospitalized patients (aged 65–95 years) with recently diagnosed type 2 diabetes mellitus were studied retrospectively in a cross-sectional study and compared with 183 subjects with prediabetes and 62 subjects without glucose metabolism abnormalities. Results: BMI (24.69±3.59 versus 23.92±3.08 and 23.56±3.25 kg/m 2 ), blood pressure, cholesterol, triglyceride, liver enzymes and prevalence of fatty liver were higher in patients with type 2 diabetes mellitus as compared with elderly subjects with prediabetes or normal glucose metabolism separately (all P <0.05). Multivariable regression analysis showed that BMI was associated positively with insulin resistance and inversely with insulin sensitivity in type 2 diabetes mellitus group (all P <0.05). Conclusion: Higher BMI was associated with increased insulin resistance and decreased insulin sensitivity in elderly Asian population with type 2 diabetes mellitus.
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Zhao et al. (2017) studied this question.
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