May 1, 1982Infection and ImmunityOpen Access

Monoclonal antibodies of four different specificities for neutralization of type 1 polioviruses

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Population

Type 1 poliovirus strains (15 strains tested)

Design

Preclinical

Authors

DHDorreth D. HumphreyCenters for Disease Control and Prevention OKOlen M. KewCenters for Disease Control and Prevention PFPaul M. FeorinoCenters for Disease Control and Prevention

Discussion

Member takes

Implication

These mAbs expand poliovirus strain-typing reagents; leaves open clinical translation from animal data.

Structured PICO

Population

Type 1 poliovirus strains (15 strains tested)

Intervention

Monoclonal antibodies from four independent hybridoma clones

Outcome

Neutralization of type 1 poliovirus strainssurrogate

Four distinct monoclonal antibodies were identified that can neutralize different subsets of type 1 poliovirus strains, providing tools for strain characterization.

Cite This Study

Humphrey et al. (1982) studied this question.

synapsesocial.com/papers/6a895fdd4c30e1095aec6dca https://doi.org/10.1128/iai.36.2.841-843.1982

View Full Paper

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Monoclonal antibodies of four different specificities for neutralization of type 1 polioviruses

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Monoclonal antibodies of four different specificities for neutralization of type 1 polioviruses

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider