Why the study?
Does rBPI23 attenuate cardiovascular depression and mortality in awake rabbits with lethal endotoxemia?
Does rBPI23 attenuate cardiovascular depression and mortality in awake rabbits with lethal endotoxemia?
rBPI23 completely prevented mortality and attenuated deleterious hemodynamic and sympathoinhibitory responses in a rabbit model of lethal endotoxemia.
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rBPI23 prevented mortality in this rabbit model; leaves open translation to human sepsis and requires clinical trials.
Koyama et al. (1995) studied this question.
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