The records of 1,500 patients with Hodgkin's disease seen at the Mayo Clinic from 1950 to 1967 were reviewed in search of any later-developing myelo-proliferative disorders. No cases of polycythemia vera, agnogenic myeloid metaplasia, or primary thrombocythemia were found in patients with pre-existent Hodgkin's disease. Three case reports of myelomonocytic leukemia (2 manifesting Auer bodies) developing 1 1/2, 5 1/2, and 18 years after the diagnosis of Hodgkin's disease are presented. Myelomonocytic leukemia does not appear to represent a transitional stage of Hodgkin's disease and is more likely related to therapy of the lymphomatous disease.
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Newman et al. (1970) studied this question.
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