Key result
Transoral robotic surgical resection successfully excised a rare intravascular papillary endothelial hyperplasia of the hypopharynx, confirming a benign diagnosis and avoiding extensive morbid surgery.
Why the study?
Intravascular papillary endothelial hyperplasia is a rare benign vascular lesion, and reporting cases in unusual sites like the hypopharynx enhances recognition and management.
Case Report (n=1)
Intravascular papillary endothelial hyperplasia (IPEH) is a rare benign vascular lesion that can mimic malignancy, and accurate histopathologic diagnosis is essential to avoid unnecessary aggressive surgical treatment.
Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson's hemangioma, is a rare benign vascular lesion characterized by an unusual pattern of endothelial proliferation within a thrombosed vessel. Histologically, IPEH is defined by prominent intraluminal papillary structures composed of a single layer of enlarged endothelial cells, lacking cytologic atypia, mitotic activity, and necrosis. Here, we report a rare case of IPEH identified in the hypopharynx of a 56-year-old male patient, incidentally, on imaging for evaluation of unrelated upper back pain. We describe the clinical presentation, histopathologic findings, differential diagnosis, and review of the current literature to enhance recognition and management of this entity in rare/unusual sites.
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Maxey et al. (2025) conducted a case report in Intravascular Papillary Endothelial Hyperplasia (IPEH) (n=1). Transoral robotic surgical resection was evaluated. Transoral robotic surgical resection successfully excised a rare intravascular papillary endothelial hyperplasia of the hypopharynx, confirming a benign diagnosis and avoiding extensive morbid surgery.
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