Transfusion of Lymphocytes

The colorless corpuscles were noted by John Hunter and described by his pupil, Hewson, in 1788. Neuman recognized in 1869 that the bone marrow was a source of their origin, and Virchow, in 1871, defined lymphocytes and demonstrated that they were formed in lymphoid tissue. Since then much has been written concerning the production of white blood corpuscles, their distribution and their function. Little, however, is known of what becomes of them, or what permits the different kinds to remain at one or another level. Bunting and Huston1have recently described the fate of the lymphocytes in rabbits. They have shown that, although the count of the circulating lymphocytes remains constant, more of the lymphocytes enter the circulation from the thoracic duct in twenty-four hours than can be accounted for by those present in the blood at any one time. They found that these cells were not destroyed in