Key result
Blood pressure responses to low-sodium and high-sodium dietary interventions were moderately inversely correlated for systolic blood pressure (correlation coefficient -0.47; 95% CI -0.51 to -0.44; P<0.0001).
Why the study?
Is there a correlation between individual blood pressure responses to low-sodium, high-sodium, and potassium supplementation interventions?
Is there a correlation between individual blood pressure responses to low-sodium, high-sodium, and potassium supplementation interventions?
Effect estimate: Correlation coefficient -0.47 (95% CI -0.51 to -0.44)
p-value: p=<0.0001
Individuals who are more sensitive to a high-sodium diet show a moderately correlated, greater blood pressure reduction from low-sodium or high-potassium interventions.
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May support sodium sensitivity phenotyping in hypertension; leaves open potassium effects and requires randomized confirmation.
Zhao et al. (2009) studied this question. Dietary sodium and potassium interventions vs. Intra-individual responses was evaluated on Correlation between blood pressure responses to low-sodium and high-sodium interventions for systolic blood pressure (Correlation coefficient -0.47, 95% CI -0.51 to -0.44, p=<0.0001). Blood pressure responses to low-sodium and high-sodium dietary interventions were moderately inversely correlated for systolic blood pressure (correlation coefficient -0.47; 95% CI -0.51 to -0.44; P<0.0001).
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