Key result
Metabolic syndrome in patients undergoing thyroidectomy was associated with increased risk of overall complications (OR 2.00) and mortality (OR 2.33).
Why the study?
Metabolic syndrome increases postoperative morbidity and mortality in other surgical settings, but its association with postoperative outcomes of thyroidectomy was not established.
Does metabolic syndrome increase the risk of adverse postoperative outcomes in patients undergoing thyroidectomy?
Cohort
Yes
Does metabolic syndrome increase the risk of adverse postoperative outcomes in patients undergoing thyroidectomy?
Odds Ratio: 2
Metabolic syndrome is associated with significantly increased risks of mortality and complications following thyroidectomy.
May inform preoperative risk counseling for thyroidectomy; leaves open causality and need for prospective intervention trials.
OBJECTIVE: Metabolic syndrome (MetS) has previously been linked to increased risk of postoperative morbidity and mortality in other surgical undertakings. Because MetS is a consequence of endocrine dysfunction, and given the thyroid's crucial role in endocrine homeostasis, we sought to evaluate the association between MetS and postoperative outcomes of thyroidectomy. METHODS: Data were acquired from the ACS-NSQIP database from years 2005 to 2017. Patients with obesity, diabetes, and hypertension were defined as having MetS. Odds ratios (OR) were obtained for outcomes to quantify risk with multivariate logistic regression. RESULTS: Outcomes significantly affected by MetS included overall complication (OR: 2.00), extended postoperative stay (OR: 1.52), medical complication (OR: 1.48), surgical complication (OR: 1.62), and mortality (OR: 2.33). CONCLUSIONS: Patients with MetS undergoing thyroidectomy are at increased risk of an increased length of stay, overall complications, and mortality.
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Elsamna et al. (2020) conducted a cohort in Thyroidectomy. Metabolic syndrome vs. No metabolic syndrome was evaluated on Overall complication (OR 2.00). Metabolic syndrome in patients undergoing thyroidectomy was associated with increased risk of overall complications (OR 2.00) and mortality (OR 2.33).
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