Key result
Continued smoking after CABG was associated with increased total mortality compared to never smokers, whereas smoking cessation was not.
Why the study?
Does smoking cessation reduce long-term mortality and the need for repeat revascularization in patients undergoing first-ever coronary artery bypass grafting?
Cohort (n=1,027)
Does smoking cessation reduce long-term mortality and the need for repeat revascularization in patients undergoing first-ever coronary artery bypass grafting?
Smoking cessation after first-ever CABG is associated with reduced long-term mortality and need for repeat revascularization compared to continued smoking.
Answers are grounded in this paper and cite their sources.
Post-CABG continued smoking signals higher mortality; supports cessation counseling yet leaves open causal benefits in randomized trials.
DESIGN: A prospective study. METHODS: We estimated the impact of smoking cessation on long-term mortality and the need for a revascularization procedure in 1027 patients undergoing a first-ever coronary artery bypass-grafting. RESULTS AND DISCUSSION: Of the 640 active smokers, 44.7% continued smoking after CABG ('current smokers'), and 55.3% quit. During a 5310 patient-years follow-up, with never smokers as the reference group, current smokers (but not quitters) experienced a significant increase in total mortality (hazard ratio 2.6, 95% confidence interval 1.0-6.6) mainly owing to increased cardiovascular mortality (hazard ratio 4.8, 95% confidence interval 1.1-21.4), as well as increased need for a repeat revascularization procedure (hazard ratio 1.7, 95% confidence interval 1.0-2.9).
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Papathanasiou et al. (2007) conducted a cohort in first-ever coronary artery bypass-grafting (n=1,027). Continued smoking vs. Never smokers was evaluated on total mortality (HR 2.6, 95% CI 1.0-6.6). Continued smoking after CABG was associated with increased total mortality compared to never smokers, whereas smoking cessation was not.
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