Key result
The size of cerebral infarction was significantly associated with the degree of ipsilateral carotid artery stenosis and the presence of ulcerated plaques (p<0.05).
Why the study?
Does carotid artery stenosis severity, intima media thickness, and plaque morphology correlate with the size of cerebral infarction in patients with acute stroke?
Observational (n=62)
No
Does carotid artery stenosis severity, intima media thickness, and plaque morphology correlate with the size of cerebral infarction in patients with acute stroke?
p-value: p=<0.05
The size of cerebral infarction is significantly related to the degree of ipsilateral carotid artery stenosis, increased intima-media thickness, and the presence of soft, ulcerated plaques.
Carotid stenosis and ulcerated plaques may link to larger infarcts in acute stroke; leaves open whether imaging informs prognosis or intervention.
Background: Duplex ultrasound is inexpensive, non-invasive and can provide functional and anatomical information about vessel stenosis and plaque morphology. Color duplex flow ultrasonography has thus become the most widely used noninvasive method of assessing extra cranial cerebrovascular occlusive disease.Objectives:To find the relation of the severity of carotid artery stenosis, intima media thickness, and atheromatous plaque morphology with the size of cerebral infarction.Patients and Methods: A prospective study, conducted from September 2010 to May 2011, in Department of Radiology in Baghdad Teaching Hospital. A total of 62 Patients with clinical & radiological (brain CT) diagnosis of acute stroke, (42 males & 20 females) had been referred from Medical & Neurological units to the Radiology Department / Ultrasound Unit for carotid arteries examination.Results: Thirty out of 62(48.4%) patients had evidence of ipsilateral carotid stenosis distributed as: 18 out of 30 patients (60%) had < 50% stenosis, 8 patients (26.7%) had 50-69% stenosis, and 4 patients (13.3%) had > 70% stenosis. Also in our study we found that homogenous hypoechoic and ulcerated plaques were more frequent in patients with large size infarcts.Conclusion: From this study we concluded that the size of cerebral infarction is related to degree of ipsilateral carotid artery stenosis, especially when the plaque is soft with irregular or ulcerated surface, and that increased intima media thickness of common carotid artery is strongly associated with stroke and its risk factors.
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Ahmed et al. (2012) conducted an observational in Acute cerebral infarction (n=62). Carotid artery stenosis and plaque morphology vs. No stenosis or normal plaque morphology was evaluated on Association between degree of ipsilateral carotid stenosis and size of cerebral infarction (p=<0.05). The size of cerebral infarction was significantly associated with the degree of ipsilateral carotid artery stenosis and the presence of ulcerated plaques (p<0.05).
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