Key result
Over a one-year period in Italy, the overall positivity rate for non-polio enteroviruses in respiratory specimens was 2.9%, with the highest burden in children under 3 years of age and three distinct epidemic waves identified.
Why the study?
Laboratory-based activities are essential for monitoring non-polio enteroviruses, but despite their significant impact, there is no international surveillance for them.
Observational (n=33,553)
Yes
This study highlights the significant burden of non-polio enteroviruses, particularly EV-D68 and echovirus-11, in pediatric respiratory infections in Italy, underscoring the need for systematic surveillance.
• Laboratory-based activities are essential for monitoring non-polio enteroviruses (NPEVs). • Despite their significant impact, there is no international surveillance for NPEVs. • This study investigated 35,532 respiratory samples for NPEV-RNA over one year. • 78.7% of NPEV-positive cases were in children under 15 years of age. • Molecular testing and sequencing revealed an EV-D68 and an echovirus-11 outbreak.
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Pellegrinelli et al. (2024) conducted an observational in Respiratory infections (ILI or ARI) (n=33,553). Non-polio enterovirus (NPEV) was evaluated on Overall NPEV positivity rate (95% CI 2.8-3.1). Over a one-year period in Italy, the overall positivity rate for non-polio enteroviruses in respiratory specimens was 2.9%, with the highest burden in children under 3 years of age and three distinct epidemic waves identified.
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