Key result
In obese individuals admitted for bariatric surgery, the 6-minute walk test distance showed an extremely significant correlation with FEV1 and MMEF 75-25 (p<0.0001).
Observational (n=50)
No
p-value: p=<0.0001
The 6-minute walk test strongly correlates with spirometric parameters in obese individuals, serving as a simple and effective prognostic tool to evaluate ventilatory status prior to bariatric surgery.
May support 6MWT as ventilatory surrogate in obese bariatric candidates; leaves open prospective validation of prognostic utility.
To evaluate Pulmonary Function Tests and 6MWT in obese individuals and to correlate 6MWT with FEV1 and MMEF 75-25 and establish the individual significance in evaluating bariatric subjects. MATERIAL AND METHOD: Prospective observational study carried out on 50 obese patients referred to PFT Lab for pre-operative investigations (admitted for planned Bariatric Surgery) after the informed consent in Department of Respiratory Medicine, Sri Aurobindo Medical College and Post Graduate Institute, Indore (MP). Biometric data (age, sex, height and weight), Pulmonary Function Tests (PFT) and Six minute walk test (6MWT) data was collected. Exclusion criteria for study is those who were not willing, unable to perform PFT/6MWT acceptably, recent cardiac event, patients with osteoarthritis or neuromuscular disorder and patients with known pre-existing respiratory illness. STATISTICAL ANALYSIS: Statistical analysis was performed using Graphpad Quick Calcs: t test calculator software. The data were reported as mean standard deviation (SD). The absolute (6MWD) in meters was used. The correlation between 6MWD and the patient's pulmonary function test were evaluated by applying unpaired 't' test. 6MWT shows extremely significant correlation with FEV1and MMEF 75-25. RESULT: There is high correlation between 6MWT and PFT in obese individuals. All the patients above normal BMI have ventilatory defect which may be due to restriction imposed by abdominal wall and chemical mediators released by adipocytes. Predicted values are calculated by Udwadia Index. CONCLUSION: 6MWT is a good prognostic tool to study ventilatory mechanism in obese individuals.
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Bharang et al. (2015) conducted an observational in Obesity (n=50). Obesity was evaluated on Correlation between 6-minute walk test distance and FEV1 / MMEF 75-25 (p=<0.0001). In obese individuals admitted for bariatric surgery, the 6-minute walk test distance showed an extremely significant correlation with FEV1 and MMEF 75-25 (p<0.0001).
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