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August 1, 1992The Journal of Experimental MedicineOpen Access

Cytotoxic T lymphocytes (CTL) against a transforming gene product select for transformed cells with point mutations within sequences encoding CTL recognition epitopes.

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Authors

NLNancy L. LillThe Ohio State UniversityMTMary J. TevethiaPennsylvania State UniversityWHWilliam HendricksonTufts University

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Lill et al. (1992) studied this question.

synapsesocial.com/papers/6a8971822c543859dc622425https://doi.org/10.1084/jem.176.2.449
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Also Consider

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  1. 1Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA.1988 · 95 citations
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  3. 3Structure of the gene of tum- transplantation antigen P198: a point mutation generates a new antigenic peptide.1990 · 151 citations
  4. 4T cell recognition of transforming proteins encoded by mutated ras proto-oncogenes1991 · 128 citations
  5. 5Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression.1983 · 249 citations