Key result
Coxsackie virus B5 infection can present as acute transverse myelitis, as demonstrated in a 6-year-old boy with rapidly progressive paraplegia and diffuse swelling of the lower spinal cord.
Case Report (n=1)
Acute transverse myelitis can be a rare clinical manifestation of Coxsackie virus B5 infection.
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May prompt Coxsackie B5 testing in pediatric transverse myelitis; hypothesis-generating case report leaves association and management open.
A 6-year-old boy developed symptoms of rapidly progressive paraplegia, associated with bowel and urinary dysfunction, but without sensory loss. Magnetic resonance imaging (MRI) examination showed diffuse swelling of the lower spinal cord on T1-weighted images. Based on the clinical presentation and MRI findings, a diagnosis of acute transverse myelitis was made. The serum titer of neutralizing antibody against Coxsackie virus B5 rose from 1/4 on admission to 1/256 1 month later and Coxsackie virus B5 was isolated from stool samples. This case serves as a reminder that acute transverse myelitis can be a rare clinical manifestation of Coxsackie virus B5 infection.
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Minami et al. (2004) conducted a case report in Acute transverse myelitis (n=1). Coxsackie virus B5 infection was evaluated on Clinical presentation and MRI findings of acute transverse myelitis. Coxsackie virus B5 infection can present as acute transverse myelitis, as demonstrated in a 6-year-old boy with rapidly progressive paraplegia and diffuse swelling of the lower spinal cord.
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