Key result
TAVR during the COVID-19 pandemic was performed safely with similar success rates (97.4% vs 99%) and 30-day survival rates (94.7% vs 98.6%) compared to the pre-pandemic period.
Why the study?
TAVR services were suspended during the first wave of COVID-19, motivating an evaluation of clinical outcomes and potential pathway delays during the pandemic.
Does performing TAVR during the COVID-19 pandemic compared to pre-pandemic times affect clinical outcomes and pathway timelines in patients with severe aortic stenosis?
Cohort (n=210)
No
Does performing TAVR during the COVID-19 pandemic compared to pre-pandemic times affect clinical outcomes and pathway timelines in patients with severe aortic stenosis?
Absolute Event Rate: 94.7% vs 98.6%
Reconfiguring the TAVR pathway during the COVID-19 pandemic allowed procedures to be performed safely without excess complications, increased 30-day mortality, or delays in workup.
Pathway reconfiguration maintained TAVR safety during COVID disruptions; leaves open optimal strategies for future crises.
AIMS: COVID-19 had a devastating impact on patients with severe aortic stenosis (AS). Like many cardiac procedures, transcatheter aortic valve replacement (TAVR) services were suspended during the first wave of COVID-19. We took the opportunity to evaluate the clinical outcomes and identify any delays at different stages of the TAVR pathway during the COVID-19 pandemic. METHODS: Prospectively collected data on 210 consecutive TAVR patients between March 2019 and March 2021 were analysed. We compared the clinical outcomes and 30-day mortality rates of TAVR cases pre-pandemic and during the pandemic. We also looked to identify any time lags from the initial referral to respective stages of the TAVR workup. RESULTS: A total of 134 patients underwent TAVR prior to the national lockdown (March 2019-March 2020), compared to 76 patients during COVID-19 (April 2020-April 2021). Success rates of TAVR were similar (99% prior to the pandemic and 97.4% during COVID-19). The 30-day survival rates were 98.6% and 94.7%, respectively. Median length of stay post TAVR was 2 days during COVID-19 and 2.5 days prior to the pandemic (p = 0.064). Patients were seen quicker in clinic (median of 33 days) during COVID-19, compared to 51 days before COVID-19 (p = 0.044). No significant difference in times from referral to discussion at TAVR multidisciplinary team (MDT) meetings, CT Aortogram and TAVR implantation, in both groups. CONCLUSIONS: Reconfiguring the patient pathway during COVID-19 allowed TAVR to be performed safely, with a similar success rate and no excess complications or increased 30-day mortality. There proved to be no delay in the respective stages of patient TAVR workup, during the pandemic.
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Tan et al. (2022) conducted a cohort in Severe aortic stenosis (n=210). TAVR during the COVID-19 pandemic vs. TAVR prior to the pandemic (March 2019-March 2020) was evaluated on 30-day survival rate. TAVR during the COVID-19 pandemic was performed safely with similar success rates (97.4% vs 99%) and 30-day survival rates (94.7% vs 98.6%) compared to the pre-pandemic period.
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