Why the study?
Does combined one-stage coronary artery and valvular surgery result in acceptable mortality in patients with significant associated valvular and coronary artery disease?
Does combined one-stage coronary artery and valvular surgery result in acceptable mortality in patients with significant associated valvular and coronary artery disease?
Combined one-stage coronary artery and valvular surgery yields encouraging mortality results in selected patients with significant associated valvular and coronary artery disease.
May support combined surgery in selected patients; hypothesis-generating and requires larger prospective studies.
Fifty patients underwent correction of one or two valvular lesions with concomitant insertion of one to three aortocoronary vein bypass grafts. Hospital mortality was 14% and late mortality was 10%. Factors influencing operative mortality were: (1) mitral valve replacement after myocardial infarction; (2) complete obstruction of a coronary artery preoperatively; (3) high left ventricular end-diastolic pressure at rest preoperatively in patients with mitral valve disease; and (4) use of a single aortocoronary graft in the presence of multiple-vessel disease. For patients with significant associated valvular and coronary artery disease, combined correction yields results that appear sufficiently encouraging, judged by mortality and follow-up, to warrant its continued use in selected cases.
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Merin et al. (1973) studied this question.
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