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Interactions of peritoneal exudate T lymphocytes from listeria-immune mice with macrophages from normal mice in the presence of heat-killed listeriae result in the induction of interleukins. The data show that Ly 1+, 23- T cells specific for listeria antigens are essential for interleukin induction and make it likely that, in addition, Ly 1+, 23+ T cells are required for optimal responses.
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Kaufmann et al. (1982) studied this question.
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