Alkylating Compounds Definition and mode of action. An alkylating agent is capable of combining with chemical groups of cell components. The biologically active alkylating agents can combine with metabolically important groups and render them relatively incapable of functioning in their usual fashion in the economy of the cell. An excellent discussion of the alkylating agents appears in the Transactions of the Cancer Conference on Comparative Clinical and Biological Effects of Alkylating Agents held by the New York Academy of Sciences in March, 1957.52 The mode of action of nitrogen mustardlike compounds is outlined in Figure 4. The first step is the . . .
No takes yet. Share an insight, caveat, or question.
Hall et al. (1962) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: