The monodentate BINOL‐derived phosphoramidite PipPhos is used as ligand for the iridium‐catalyzed asymmetric hydrogenation of 2‐ and 2,6‐substituted quinolines. If tri‐ortho‐tolylphosphine and/or chloride salts are used as additives enantioselectivities are strongly enhanced up to 89%. NMR indicates that no mixed complexes are formed upon addition of tri‐ortho‐tolylphosphine.
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Mršić et al. (2008) studied this question.
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