Key result
Long non-coding RNAs are closely related to the pathogenesis and regulation of diabetic peripheral neuropathy.
Why the study?
Diabetic peripheral neuropathy is a common chronic complication of diabetes mellitus, and lncRNAs have recently been found to be closely related to neurological, endocrine, and metabolic disorders.
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This review summarizes recent research on the role of long non-coding RNAs in the pathogenesis and regulation of diabetic peripheral neuropathy.
Long non-coding RNAs (lncRNAs) are a group of non-coding RNAs longer than 200 nucleotides, which are defined as transcripts. The lncRNAs are involved in regulating gene expression at epigenetic, transcriptional, and post-transcriptional levels. Recent studies have found that lncRNA is closely related to many diseases like neurological diseases, endocrine and metabolic disorders. Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus. In this review, we highlight the latest research related to lncRNAs in DPN.
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Wu et al. (2020) conducted a review in Diabetic Peripheral Neuropathy. Long non-coding RNAs (lncRNAs) was evaluated. Long non-coding RNAs are closely related to the pathogenesis and regulation of diabetic peripheral neuropathy.
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