Selenium-dependent glutathione peroxidase (GPX1) is a cytosolic antioxidant enzyme that neutralizes H2O2 to water and oxygen ([1][1]). A GPX1 Pro→Leu polymorphism exists at codon 198, with the variant Leu allele being less responsive than the common Pro allele to the stimulation of enzyme activity
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Ahn et al. (2005) studied this question.
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