Background: Blood oxidant profile affects tumor cell eradication in cancer patients undergoing thermotherapy. Objective: The study objectives were the determination of the blood oxidant/antioxidant balance in colorectal cancer (CRC) before and after the XELOX regimen combined with Bevacizumab, and also the effect of treatment on the oxidative stress markers during the first cycle of chemotherapy. Methods: In this case-control study, 50 healthy controls and 41 colorectal patients were recruited at Popular Hospital Establishment and Avicne Medical Clinic (Maghnia city, Algeria) during 2019. Blood samples were collected from participants before and after treatment. To determine the fluctuations of redox status vis--vis of treatment, levels of oxidant and antioxidant parameters were measured using spectrophotometry. Data were analyzed using independent samples t-test and Pearson's correlation coefficients.
No takes yet. Share an insight, caveat, or question.
Badid et al. (2021) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: