What question did this study set out to answer?

To evaluate the clinical effectiveness, safety, and patient acceptability of medication abortion when mifepristone is dispensed directly by community pharmacists.

March 10, 2021Obstetrics and GynecologyOpen Access

Medication Abortion With Pharmacist Dispensing of Mifepristone

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Authors

DGDaniel GrossmanUniversity of California, San Francisco CBC. Finley BabaReproductive Science Center SKShelly KallerReproductive Science Center

Discussion

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Implication

Randomized trial demonstrates high effectiveness and satisfaction with pharmacist-dispensed mifepristone for medication abortion, suggesting safe expanded community pharmacy access.

Key Points

To evaluate the clinical effectiveness, safety, and patient acceptability of medication abortion when mifepristone is dispensed directly by community pharmacists.
Conducted an interventional clinical trial (ClinicalTrials.gov, NCT03320057) across eight clinical sites and pharmacies in California and Washington State from July 2018 to March 2020.
Enrolled 266 patients counseled for medication abortion who received pharmacy-dispensed oral mifepristone (200 mg) followed 24–48 hours later by buccal misoprostol (800 mcg).
Evaluated clinical outcomes and adverse events via medical records, collected patient satisfaction through surveys on days 2 and 14, and assessed predictors of satisfaction using multivariable logistic regression.
Complete medication abortion occurred in 93.5% of participants with available outcome data (243/260; 95% CI, 89.7–96.1%).
Adverse events occurred in 1.5% of participants (4/260; 95% CI, 0.4–3.9%), with none classified as serious or related to pharmacist dispensing.
Satisfaction with the pharmacy experience was reported by 91.3% on day 2 (95% CI, 87.1–94.4%), and high pharmacy satisfaction significantly increased the odds of overall abortion satisfaction (adjusted OR, 2.96; 95% CI, 1.38–6.32).

Cite This Study

Grossman et al. (2021) studied this question.

synapsesocial.com/papers/6a89901cabe412682d92ef28 https://doi.org/10.1097/aog.0000000000004312

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Implication

Randomized trial demonstrates high effectiveness and satisfaction with pharmacist-dispensed mifepristone for medication abortion, suggesting safe expanded community pharmacy access.

Medication Abortion With Pharmacist Dispensing of Mifepristone

Discussion

Member takes

Implication

Key Points

Cite This Study

Medication Abortion With Pharmacist Dispensing of Mifepristone

Discussion

Member takes

Implication

Key Points

Cite This Study

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