A new error of tyrosine metabolism: tyrosinosis. The intermediary metabolism of tyrosine and phenylalanine

THE object of the present paper is to describe an addition to the few known errors of metabolism. That the condition here described for the first time is not common is shown by the following observation. The only way in which it may be routinely discovered is by following up urines reported as giving a doubtfully positive sugar test. Dr Blatherwick, the head of the laboratory of the Metropolitan Life Insurance Co., who was present when some of these findings were presented in Chicago in 1930, has since then followed up 14,753 urines which contained 0-3 % sugar according to Benedict's picric acid method.