Key result
Port site injection and intraperitoneal instillation of bupivacaine significantly reduced post-operative pain up to 24 hours compared to no infiltration.
Why the study?
Effective postoperative pain control is essential to prevent morbidity or mortality after surgery, prompting assessment of port site injection and intraperitoneal bupivacaine after laparoscopic cholecystectomy.
Does port site injection and intraperitoneal instillation of bupivacaine reduce post-operative pain after laparoscopic cholecystectomy in patients with symptomatic cholelithiasis?
Population
180 patients undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis
Comparison
Port site bupivacaine vs port site plus intraperitoneal bupivacaine vs no local infiltration
Design
Controlled study
Follow-up
24 hours
Authors
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May support bupivacaine for post-cholecystectomy pain control; hypothesis-generating from Level 3 data and needs RCT confirmation.
Does port site injection and intraperitoneal instillation of bupivacaine reduce post-operative pain after laparoscopic cholecystectomy in patients with symptomatic cholelithiasis?
Instillation of bupivacaine at port sites provides effective post-operative pain control up to 24 hours after laparoscopic cholecystectomy, regardless of timing or intraperitoneal addition.
Nippun Roy (2020) studied symptomatic cholelithiasis (n=180). Bupivacaine vs. No local infiltration was evaluated on Post-operative pain scores. Port site injection and intraperitoneal instillation of bupivacaine significantly reduced post-operative pain up to 24 hours compared to no infiltration.
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