Recognized Obstructive Sleep Apnea is Associated With Improved In‐Hospital Outcomes After ST Elevation Myocardial Infarction
Key result
Recognized obstructive sleep apnea in patients with ST-elevation myocardial infarction was associated with decreased in-hospital mortality (adjusted OR 0.78; 95% CI 0.73-0.84).
Why the study?
Does recognized obstructive sleep apnea affect in-hospital mortality in patients hospitalized for ST-elevation myocardial infarction?
Population
1,850,625 patients with a primary discharge diagnosis of ST-elevation myocardial infarction from a…
Comparison
Recognized obstructive sleep apnea vs No recognized obstructive sleep apnea
Design
Cohort
Follow-up
In-hospital
Authors
Discussion
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Implication
Highlights a paradoxical survival benefit in STEMI; leaves open whether this reflects true ischemic preconditioning.
Study Design
Type
Cohort (n=1,850,625)
Multicenter
Yes
Structured PICO
Does recognized obstructive sleep apnea affect in-hospital mortality in patients hospitalized for ST-elevation myocardial infarction?
P
Population
1,850,625 patients hospitalized with a primary discharge diagnosis of ST-elevation myocardial infarction between 2003 and 2011.
E
Exposure
Recognized obstructive sleep apnea (OSA) (n=24,623, 1.3%)
C
Comparator
No recognized obstructive sleep apnea
O
Outcome
In-hospital mortalityhard clinical
Main Result
Odds Ratio: 0.78 (95% CI 0.73–0.84)
Recognized obstructive sleep apnea is paradoxically associated with lower in-hospital mortality among patients presenting with ST-elevation myocardial infarction.
Cite This Study
Mohananey et al. (2017) conducted a cohort in ST-elevation myocardial infarction (n=1,850,625). Obstructive sleep apnea vs. Patients without obstructive sleep apnea was evaluated on In-hospital mortality (OR 0.78, 95% CI 0.73-0.84). Recognized obstructive sleep apnea in patients with ST-elevation myocardial infarction was associated with decreased in-hospital mortality (adjusted OR 0.78; 95% CI 0.73-0.84).