Goldfish acclimated for minimum periods of 3 weeks to 5, 15, 25 and 35°C exhibited significant changes in circulating leucocyte types and numbers. Total leucocyte, lymphocyte, neutrophil and eosinophil levels increased significantly between 5 and 25°C, as did their relative contributions to the total leucocyte population. Thrombocyte and blast cell counts increased non‐significantly, while variations in monocyte and basophil levels were inconsistent. Between 25 and 35° C, lymphocyte numbers fell sharply, while neutrophil concentrations remained essentially constant as did those of thrombocytes. Response to an intraperitoneally administered mitogen, phytohaemagglutinin, was delayed and reduced at 5° C compared with 25° C.
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Dunn et al. (1989) studied this question.
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