The additive effect of poly(ethylene oxide) (PEO) in several nucleophilic reactions, such as the oxidation of trans‐stilbene with potassium permanganate, the alkylation of potassium acetate and diethyl benzylsodiomalonate as well as the Williamson reaction of sodium phenoxide with alkyl bromides was investigated and compared with that of dibenzo‐18‐crown‐6 (crown ether). A marked effect by PEO was observed under certain conditions, which was explained by a cooperative coordination of the oxygen atoms of PEO with metal cations promoting ion dissociation and resulting in the observed remarkable rate acceleration.
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Hirao et al. (1978) studied this question.
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