Measurement of Seminal plasma peptidoglycan recognition protein-1 (PGLYRP‐1) protein infertile males as a measure of leukocytospermia and bad seminal fluid parameters

Human peptidoglycan recognition protein-1 (PGLYRP‐1) protein molecule activation in the semen of infertile patients has been suggested to induce a negative impact on seminal fluid analysis. 176 infertile patients included in this study were tested for seminal fluid analysis, Endtz test, and PGLYRP‐1 in seminal plasma using enzyme-linked immunosorbent assay (ELISA) technology. PGLYRP‐1 is evident in the seminal plasma of infertile men and is statistically different according to the type of infertility. The concentration of PGLYRP-1 in the semen is directly proportional to the presence of leukocytes (Endtz test), which is reflected negatively on the quality of the semen. To the best of our knowledge, this study has not been done in Iraq or elsewhere. The presence of PGLYRP-1 protein in the semen may be evidence of leukocytospermia that may be related to bad quality for semen across infertile men with higher sensitivity than the Endtz test.