January 1, 2017Russian Journal of Archive of Pathology

Morphological features of the myocardium of the atrial appendages in patients with different forms of atrial fibrillation

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Atrial fibrillation. Intervention: Atrial fibrillation (paroxysmal, persistent, or long-standing persistent) vs. Sinus rhythm without history of AF. Primary outcome: Morphological features of the myocardium of the atrial appendages.

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Population

Adult patients with paroxysmal, persistent, or long-standing persistent atrial fibrillation and a comparison…

Design

Cross-sectional

Key result

Patients with paroxysmal atrial fibrillation exhibited opposite morphological changes in cardiomyocyte hypertrophy, amyloidosis, and myofibrillar loss compared to those with long-standing persistent AF.

Authors

ТSТ. V. Sukhacheva VVV.A. Vaskovsky АРА. Ш. Ревишвили

Discussion

Member takes

Overview

Distinct remodeling patterns distinguish paroxysmal from persistent AF; extends phenotyping but leaves open progression biomarkers and management implications.

Study Design

Type

Observational

Structured PICO

Population

Adult patients with paroxysmal, persistent, or long-standing persistent atrial fibrillation compared to a control group with sinus rhythm.

Comparator

Comparison group patients with sinus rhythm without history of AF

Outcome

Morphological features of the myocardium of the atrial appendages including myocardial fibrosis, cardiomyocyte diameter, lipomatosis, amyloidosis, and myofibril contentsurrogate

Different clinical forms of atrial fibrillation are associated with distinct patterns of cellular remodeling and correlations between cardiomyocyte hypertrophy and left atrial enlargement.

Cite This Study

Sukhacheva et al. (2017) conducted an observational in Atrial fibrillation. Atrial fibrillation (paroxysmal, persistent, or long-standing persistent) vs. Sinus rhythm without history of AF was evaluated on Morphological features of the myocardium of the atrial appendages. Patients with paroxysmal atrial fibrillation exhibited opposite morphological changes in cardiomyocyte hypertrophy, amyloidosis, and myofibrillar loss compared to those with long-standing persistent AF.

synapsesocial.com/papers/6a89ac87991508d05dc9942e https://doi.org/10.17116/patol20177943-12

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January 1, 2017Russian Journal of Archive of Pathology

Morphological features of the myocardium of the atrial appendages in patients with different forms of atrial fibrillation

View Full Paper

Ask AI

Bookmark

Population

Adult patients with paroxysmal, persistent, or long-standing persistent atrial fibrillation and a comparison…

Design

Cross-sectional

Key result

Authors

ТSТ. V. Sukhacheva VVV.A. Vaskovsky АРА. Ш. Ревишвили

Discussion

Member takes

Overview

Distinct remodeling patterns distinguish paroxysmal from persistent AF; extends phenotyping but leaves open progression biomarkers and management implications.

Study Design

Type

Observational

Structured PICO

Population

Adult patients with paroxysmal, persistent, or long-standing persistent atrial fibrillation compared to a control group with sinus rhythm.

Comparator

Comparison group patients with sinus rhythm without history of AF

Outcome

Morphological features of the myocardium of the atrial appendages including myocardial fibrosis, cardiomyocyte diameter, lipomatosis, amyloidosis, and myofibril contentsurrogate

Different clinical forms of atrial fibrillation are associated with distinct patterns of cellular remodeling and correlations between cardiomyocyte hypertrophy and left atrial enlargement.

Cite This Study

synapsesocial.com/papers/6a89ac87991508d05dc9942e https://doi.org/10.17116/patol20177943-12

View Full Paper

Ask AI

Bookmark