Key result
A novel synchronous spectrofluorimetric method successfully estimated bisoprolol fumarate and ivabradine in spiked human urine with percentage recoveries of 99.95% and 99.98%, respectively.
Population
Pharmaceutical dosage forms and spiked human urine samples
Design
Analytical assay and method development study
Authors
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May enable drug monitoring in biological fluids; leaves open clinical validation before routine use.
A novel, green synchronous spectrofluorimetric method was developed for the simultaneous estimation of bisoprolol and ivabradine in pharmaceutical and biological matrices.
Elkheir et al. (2022) studied this question. First derivative synchronous spectrofluorimetric analysis was evaluated on Simultaneous estimation of bisoprolol fumarate and ivabradine. A novel synchronous spectrofluorimetric method successfully estimated bisoprolol fumarate and ivabradine in spiked human urine with percentage recoveries of 99.95% and 99.98%, respectively.
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