Synthesis of Carbocyclic and Heterocyclic β-Aminocarboxylic Acids

In consequence of their biological e , conformationally carbocyclic β -amino acids have generated great among synthetic and medicinal chemists in the past 2 , and they have become a hot topic in organic and chemistry. These compounds are found in natural and antibiotics. They are also considered important for pharmacologically interesting β -lactams and bioactive compounds. Certain carbocyclic β -amino acids, ≠.g., cispentacin , icofungipen , and BAY Y9379 , noteworthy antifungal or antibacterial activities, while , a phenyl-substituted cyclohexene amino ester, is an .