What question did this study set out to answer?

To identify the clinical symptom patterns and abnormal laboratory findings present in patients with colorectal cancer prior to definitive diagnosis.

May 5, 2025Bangladesh Journal of MedicineOpen Access

Prediagnostic Clinical Presentations and Abnormal Laboratory Reports in Patients of Colorectal Carcinoma: A 5 years’ Experience from a Tertiary Care Hospital of Bangladesh

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Authors

MHMd Shakhawat Hossain MMaknunnahar MAMd Mahfuj Ul Anwar

Discussion

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Overview

Cross-sectional study reveals frequent abdominal pain, anemia, and elevated inflammatory markers in colorectal cancer patients, highlighting opportunities for earlier referral and diagnosis.

Key Points

To identify the clinical symptom patterns and abnormal laboratory findings present in patients with colorectal cancer prior to definitive diagnosis.
Cross-sectional study conducted at the gastroenterology department of Rangpur Medical College, Rangpur, Bangladesh, between January 2019 and December 2023.
Evaluated prediagnostic clinical records, laboratory profiles, and imaging results for 1,150 patients with colonoscopy- and histopathologically proven colorectal carcinoma (73.47% male, 26.52% female).
The most common prediagnostic symptoms were abdominal pain (77.39%, n=890), altered bowel habits (46.95%, n=540), anemia/pallor (29.56%, n=340), weight loss (23.21%, n=267), and rectal bleeding (20.69%, n=238).
Common laboratory abnormalities included elevated C-reactive protein (65.56%, n=754), elevated erythrocyte sedimentation rate (51.22%, n=589), and decreased hemoglobin (47.04%, n=541).
Significant diagnostic delays occurred: 50.86% (n=585) presented between 6 months and 2 years after symptom onset, and 35% consulted three or more physicians before confirmation.

Cite This Study

Hossain et al. (2025) studied this question.

synapsesocial.com/papers/6a89b75e6fc170cbc2fbbb1c https://doi.org/10.3329/bjm.v36i2.79815

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May 5, 2025Bangladesh Journal of MedicineOpen Access

Prediagnostic Clinical Presentations and Abnormal Laboratory Reports in Patients of Colorectal Carcinoma: A 5 years’ Experience from a Tertiary Care Hospital of Bangladesh

View Full Paper

Ask AI

Bookmark

Authors

MHMd Shakhawat Hossain MMaknunnahar MAMd Mahfuj Ul Anwar

Discussion

Member takes

Overview

Cross-sectional study reveals frequent abdominal pain, anemia, and elevated inflammatory markers in colorectal cancer patients, highlighting opportunities for earlier referral and diagnosis.

Key Points

To identify the clinical symptom patterns and abnormal laboratory findings present in patients with colorectal cancer prior to definitive diagnosis.
Cross-sectional study conducted at the gastroenterology department of Rangpur Medical College, Rangpur, Bangladesh, between January 2019 and December 2023.
Evaluated prediagnostic clinical records, laboratory profiles, and imaging results for 1,150 patients with colonoscopy- and histopathologically proven colorectal carcinoma (73.47% male, 26.52% female).
The most common prediagnostic symptoms were abdominal pain (77.39%, n=890), altered bowel habits (46.95%, n=540), anemia/pallor (29.56%, n=340), weight loss (23.21%, n=267), and rectal bleeding (20.69%, n=238).
Common laboratory abnormalities included elevated C-reactive protein (65.56%, n=754), elevated erythrocyte sedimentation rate (51.22%, n=589), and decreased hemoglobin (47.04%, n=541).
Significant diagnostic delays occurred: 50.86% (n=585) presented between 6 months and 2 years after symptom onset, and 35% consulted three or more physicians before confirmation.

Cite This Study

Hossain et al. (2025) studied this question.

synapsesocial.com/papers/6a89b75e6fc170cbc2fbbb1c https://doi.org/10.3329/bjm.v36i2.79815

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