New pharmacological stress echocardiography using combined olprinone with low-dose dobutamine to detect myocardial viability

33 subjects (29 with ischemic heart disease, 4 healthy volunteers), mean age 56.1 years, 27 males. Key exclusions: unstable angina, severe ventricular arrhythmia, acute myocarditis, acute pulmonary embolism/infarction, severe aortic stenosis.

Dobutamine 10 μg/kg/min combined with olprinone 2 μg/kg/min administered intravenously

Dobutamine 10 μg/kg/min alone (sequential comparison in the same patients)

Wall motion score (WMS) evaluated by 30-segment model and left ventricular (LV) work calculated from end-systolic pressure and stroke volumesurrogate