Why the study?
Does percutaneous MitraClip implantation improve clinical outcomes and survival compared to surgical correction in patients with severe mitral regurgitation?
Population
Patients with severe organic and/or functional mitral regurgitation. Meta-analysis of 4 publications.
Comparison
Percutaneous mitral valve edge-to-edge repair… vs Surgical mitral valve repair or replacement.
Design
Meta-analysis
Follow-up
12 months
Authors
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Comparable mortality despite higher residual MR supports MitraClip as surgical alternative; extends meta-analytic evidence for non-inferior survival in severe MR.
Does percutaneous MitraClip implantation improve clinical outcomes and survival compared to surgical correction in patients with severe mitral regurgitation?
MitraClip demonstrates non-inferior clinical outcomes and survival compared to conventional surgery for severe mitral regurgitation, despite higher residual MR and a higher baseline risk profile.
Wan et al. (2013) studied this question.
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