March 1, 1984AJP Regulatory Integrative and Comparative Physiology

Raphe neurons with sympathetic-related activity: baroreceptor responses and spinal connections

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Population

Cat medullary raphe neurons

Design

Preclinical

Authors

SMShaun F. MorrisonOregon National Primate Research Center GGG. L. GebberMichigan State University

Discussion

Member takes

Implication

No basis to alter human baroreflex therapies; leaves open translational role of raphe neuron subtypes in sympathoinhibition.

Structured PICO

Population

Cat medullary raphe neurons (n=190 units with activity related to inferior cardiac sympathetic nerve discharge)

Intervention

Baroreceptor reflex activation via elevated carotid sinus pressure and time-controlled collision test for antidromic activation

Outcome

Neuronal response (excitation or inhibition) and spinal connectionssurrogate

Type I medullary raphe neurons in cats are excited by baroreceptor activation and may mediate sympathoinhibition, receiving input from the generator of sympathetic nerve discharge rhythm.

Cite This Study

Morrison et al. (1984) studied this question.

synapsesocial.com/papers/6a89c1071acf8e321fbd67e2 https://doi.org/10.1152/ajpregu.1984.246.3.r338

View Full Paper

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Bookmark

Raphe neurons with sympathetic-related activity: baroreceptor responses and spinal connections

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Raphe neurons with sympathetic-related activity: baroreceptor responses and spinal connections

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider