Why the study?
Are there differences in autoantibody levels between MS patients and control patients with other neurological diseases?
Are there differences in autoantibody levels between MS patients and control patients with other neurological diseases?
Answers are grounded in this paper and cite their sources.
There is no significant difference in autoantibody levels between patients with multiple sclerosis and those with other neurological diseases.
Serum and CSF specimens of 30 MS patients and 30 age- and sex-matched control patients with other neurological diseases were tested for autoantibodies. Indirect immunofluorescense was used to detect smooth muscle antibodies and antinuclear antibodies in the serum. Antibodies against DNA and RNA in the serum and CSF were tested by solid phase radioimmunoassays. No significant differences in autoantibody levels were found between MS and control patients.
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Hyypiä et al. (1982) studied this question.
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