Recent developments in leukemia. Further observations on the immunofluorescence of cells in human leukemia

0 from several laboratories is that the "virus-like particles" observed by thin-section electron microscopy in the plasma of humans with acute leukemia may play a role in the etiology of this disease. Recent reviews by Dmochowski2 and especially Anderson1 emphasize the necessity for using thin-sectioning techniques in electron microscopic search for these particles because misleading submicroscopic structures, which to the untrained eye may simulate "virus-like particles" and mycoplasma species, may cause confusion if the negative staining technique is relied upon.