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May 1, 2005Arthritis & Rheumatism

Type I collagen α1 Sp1 transcription factor binding site polymorphism is associated with reduced risk of hip osteoarthritis defined by severe joint space narrowing in elderly women

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Authors

KLKe LianFujian Medical UniversityJZJoseph M. ZmudaUniversity of PittsburghMNMichael C. NevittBoston University

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Lian et al. (2005) studied this question.

synapsesocial.com/papers/6a89ca67abe412682d93022fhttps://doi.org/10.1002/art.21011
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lack of association between osteoarthritis of the hip and gene polymorphisms ofVDR, COL1A1, andCOL2A1 in postmenopausal women1998 · 43 citations
  2. 2Relation of Alleles of the Collagen Type Iα1 Gene to Bone Density and the Risk of Osteoporotic Fractures in Postmenopausal Women1998 · 424 citations
  3. 3The associations of bone mineral density and bone turnover markers with osteoarthritis of the hand and knee in pre- and perimenopausal women1999 · 166 citations
  4. 4A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality2001 · 470 citations
  5. 5Mutations in collagen genes: causes of rare and some common diseases in humans1991 · 485 citations