Why the study?
Does a dietary vitamin K-guided strategy improve the achievement of target INR in outpatients with recent out-of-range INR compared to conventional anticoagulant prescription changes?
Population
132 outpatients with a recent international normalized ratio outside the therapeutic target, predominantly…
Comparison
Dietary vitamin K-guided strategy based on… vs Conventional approach based on changes in…
Design
RCT, randomized
Follow-up
90 days
Authors
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Supports vitamin K-guided INR management in unstable outpatients; extends RCT evidence for dietary strategies beyond conventional dose adjustment.
Does a dietary vitamin K-guided strategy improve the achievement of target INR in outpatients with recent out-of-range INR compared to conventional anticoagulant prescription changes?
A dietary vitamin K-guided strategy is a feasible and safe alternative to conventional dose adjustments that significantly improves the likelihood of achieving target INR levels at 90 days.
Assis et al. (2009) studied this question.
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