Why the study?
The study was conducted to evaluate oncologic outcomes in patients with PT3aNxM0 renal cell carcinoma after radical nephrectomy, examine specific PT3a subgroups, and determine predictors of recurrence, metastasis, and mortality.
Population
94 patients with stage PT3a renal cell carcinoma who underwent radical nephrectomy
Design
Retrospective cohort study
Follow-up
Mean 48.1 ± 25.5 months
Authors
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Advanced Fuhrman grade and sarcomatoid change may identify higher-risk pT3a RCC; leaves open need for prospective validation before changing surveillance.
Advanced nuclear Fuhrman's grade and simultaneous involvement of the renal vein and perinephric fat independently predict mortality in patients with stage PT3aNxM0 renal cell carcinoma after radical nephrectomy.
Soltani et al. (2023) studied this question.
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