Cyclodextrin-Scaffolded Glycoclusters

This is the authors' abstract. We don't add key points for this paper.

Fully carbohydrate glycoclusters featuring a hydrophobic cavity and an outer seven-fold symmetric saccharide patch (see picture) have been efficiently prepared in two steps from readily available sugar isothiocyanates and per-(6-amino-6-deoxy)-β-cyclodextrin. The flexiblility of this strategy, compatible with the use of alkyl or aryl spacers, and its potential for the design of specific-site-delivery drug carriers are outlined.