Why the study?
Endovascular treatment of ascending aorta pathologies has not been incorporated into routine clinical practice.
The Endo-Bentall procedure, utilizing an endovascular valve-carrying conduit, is proposed as a conceptual approach that could potentially treat up to two-thirds of patients with acute type A aortic dissection.
May expand endovascular options in acute aortic dissection; hypothesis-generating and requires prospective validation before practice change.
The endovascular treatment of pathologies of the ascending aorta has not been incorporated into routine clinical practice. The aim of this article is to provide an overview of the endovascular treatment of pathologies of the ascending aorta, particularly type A aortic dissection. A thorough analysis and discussion of anatomical, physiological, clinical and technical challenges, and obstacles is performed. Conventional straight stent-grafts alone are not capable of fixing the entire complex underlying problem in the vast majority of patients with acute type A aortic dissection. An endovascular valve-carrying conduit consisting of a proximal transcatheter aortic valve connected to a covered stent-graft would be able to close a primary entry tear in the ascending aorta, ensure coronary perfusion, initiate true lumen expansion, treat malperfusion, treat aortic regurgitation, drain any pericardial effusion through a transapical approach, and possibly stabilize the distal aorta. Two thirds of all patients with acute aortic dissection are potential candidates for endovascular treatment, and the concept may help to significantly improve survival in patients with acute aortic dissection.
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Kreibich et al. (2020) studied this question.
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