The Potency of Guava Psidium Guajava (L.) Leaves as a Functional Immunostimulatory Ingredient

The potential of natural substances to improve the immune system has long been the subject of investigation. The purpose of this research was to study Guava (Psidium guajava L.) leaf extract as a functional ingredient for immunostimulant. The study used water and ethanol as solvents to obtain optimum active compounds of the extracts. The result showed that the higher the content of phenol total was found in the extract, the higher the stimulation index value was obtained for both solvents. However, the stimulation index value was not only influenced by antioxidant activity. The reason was that the type of active compound in Guava leaf extract responsible for immunostimulatory activity was probably not only polyphenolic antioxidant.