Why the study?
Does left ventricular recovery post-TAVI improve survival in patients with severe baseline LV dysfunction?
Does left ventricular recovery post-TAVI improve survival in patients with severe baseline LV dysfunction?
Left ventricular recovery after TAVI in patients with severe baseline dysfunction is common and is associated with improved 3-year survival.
n this issue of EuroIntervention, Witberg et al 1 analyse data from the AMTRAC Registry to examine the incidence, predictors and outcomes of left ventricular (LV) recovery post-transcatheter aortic valve implantation (TAVI).Of 10,872 TAVI patients included in this 17-centre registry from Europe and Israel, 914 had severe LV dysfunction prior to TAVI (LV ejection fraction [LVEF] ≤30%).LVEF recovered by ≥10% in 59.5% of patients and normalised to ≥50% in approximately one-quarter of patients.Compared to patients with a baseline LVEF >30%, no LV recovery was associated with increased mortality, LV recovery with similar mortality, and LV normalisation with lower mortality at 3 years.The miraculous nature of these results deserves further examination.
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Dauerman et al. (2024) studied this question.
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