Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 1996Gynecological Endocrinology

Women with PCOS had significantly higher LDL-C (3.61 +/- 1.19 vs. 3.08 +/- 0.82 mmol/l, p < 0.05) and total cholesterol (5.55 +/- 1.24 vs. 4.99 +/- 0.88 mmol/l, p < 0.05) compared to controls, independent of BMI and ethnicity.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Do women with PCOS have a more atherogenic lipid profile compared to healthy controls independent of BMI and ethnicity?

Population

1,454 women, comprising 26 women with polycystic ovary syndrome and 1,428 female control participants from…

Comparison

Polycystic ovary syndrome (PCOS) diagnosis vs Female control participants without PCOS

Design

Case-control

Authors

SESigrid von EckardsteinAEArnold von EckardsteinHBH. G. Bender

Discussion

Loading...

Member takes

Overview

Supports lipid assessment in PCOS; confirms independent dyslipidemia but leaves CV risk implications open.

Structured PICO

Do women with PCOS have a more atherogenic lipid profile compared to healthy controls independent of BMI and ethnicity?

P
Population
1,454 women, comprising 26 women with polycystic ovary syndrome (PCOS) and 1,428 female control participants from the Prospective Cardiovascular Münster (PRO-CAM) study who did not use hormonal contraceptives and were of similar age.
I
Intervention
Polycystic ovary syndrome (PCOS) diagnosis
C
Comparator
Female control participants without PCOS
O
Outcome
Lipid profile (total cholesterol, LDL-C, triglycerides, HDL-C)surrogate

Women with PCOS have a higher prevalence of dyslipidemia, including elevated LDL-C and triglycerides, independent of excess weight.

Cite This Study

Eckardstein et al. (1996) studied this question.

synapsesocial.com/papers/6a89d3d52a1069eaeccbe9dchttps://doi.org/10.3109/09513599609012817
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dyslipidemia in women with polycystic ovary syndrome: incidence, pattern and predictors2010 · 81 citations
  2. 2Dyslipidemia in women with polycystic ovary syndrome2013 · 188 citations
  3. 3Altered Composition of High Density Lipoproteins in Women with the Polycystic Ovary Syndrome<sup>1</sup>1997 · 86 citations
  4. 4Prevalence of Dyslipidaemia and Pre-Diabetes Among Women with Polycystic Ovary Syndrome (PCOS): Do We Overestimate Cardiovascular Risk?2019 · 11 citations
  5. 5Lipid and lipoprotein profile in women with polycystic ovary syndromeThis article is one of a selection of papers published in the special issue Bridging the Gap: Where Progress in Cardiovascular and Neurophysiologic Research Meet.2008 · 61 citations